Research-grade linker tools
Linker properties for PROTAC and ADC
Length, flexibility, MW, logP, cleavability, and 3D conformation—one platform for linker design.
Research and education only. Not medical advice.
Go to Linker Properties to get started.
How it works
Search or enter sequence
Use the search above or go to the main calculator to enter linker SMILES or structure.Peptide Properties
Get properties & dose
Get length, flexibility, MW, logP, solubility, cleavability.
Verify purity
View 3D conformation and export SDF, PDB, PNG, PDF.Open Verify →
Linker → properties
Enter linker SMILES or structure. Get length, flexibility, MW, logP, solubility, cleavability. 3D viewer and export SDF, PDB, PNG, PDF.
3D Structure Viewer — Linker
View linker and ternary complex structures in-site (rotate, zoom, measure, export).
Calculator · 3D Viewer · Export
Linker properties (length/flexibility/MW), flexibility score, hydrophobicity; linker 3D conformation, PROTAC/ADC linker fit; export formats and linker library export. Calculator → Tools →
Linker Properties (flexibility)
SMILES → length, flexibility, MW, logP, solubility.
Linker Library
Common linkers (PEG, VC, cleavable) with SMILES and properties.
Batch SMILES
Multiple SMILES; table and CSV export.
Hydrophobicity Calculation
Hydrophobicity and physicochemical properties from sequence or structure.
Linker 3D Conformation
View linker 3D. Load PDB/SDF, measure, export.
PROTAC Linker Fit
Multi-frame 3D and linker conformation in ternary complex.
ADC Linker Fit
Load ADC/linker PDB. View linker–payload fit, export.
Export Formats
SDF, PDB, PNG. Download and cite.
Linker Library Export
Export linker library or common linkers list (SDF/CSV).
Docs
Getting started, linker types, data sources (ChEMBL), tutorials.
Pricing
Free tier for research. Pro & Enterprise for teams and API.
Calculation standards & reproducibility — IUPAC, Bjellqvist (pI), Expasy ProtParam. All results traceable and citable.
For peptide purity verification (Janoshik), see Verify. For Visual Linker quality control, use your preferred third-party lab.